Some Licensing Examples
This is a random sampling of some of the nearly 1,500 licenses in the database.
Licensed technologies are listed alphabetically with licensee(s) and a general comment about development status. Federal bio-technology transfer is relatively new and there are many more products in development than have reached the market.
3D cell culture (organoids) - Synthecon - on market
adeno-associated virus (AAV) gene therapy vectors (development) - Theragen/Warner-Lambert - Targeted Genetics (AHP) - GenVec - Genetic Therapy Inc.
antisense drugs (phosphorothioates) - Gilead Sciences - Isis Pharm. - Hybridon/Roche - Gen-Probe (Chugai Pharm.) - Lynx Therapeutics - PharmaGenics - clinical trials
apolipoprotein E - Monoclonetics - development
B3-PE immunotoxins - Boehringer Mannheim - clinical trials
basement membrane matrix - Genome Therapeutics - development
bioreactors, hollow fiber - CD Medical - Bio-Response - Monsanto - Applied Membrane Technology - Microgon - Cellco - Cellex Biosciences - on market
butyryl cholinesterase (development) - Pharmavene
capillary zone electrophoresis - PATCO (gene seq.) - Lachat Instruments - development
carcinoembryonic antigen (CEA) cancer vaccines - Therion - clinical trials
catheters, fiber optic - Clinical Instruments - on market
cell cytometers - Cell Robotics - Cytomation - development
cholecystokinin (CCK) receptor - Berlex/Schering AG - development
cholesterol cleavage enzymes (cardiovascular) - Molecular Probes - development
cholinesterase inhibitors (neurological) - Pharmavene - development
cyclic peptides - Diatech Inc. - development
cyclodextrins, amorphous (drug deliviery) - Janssen Pharmaceutical/Johnson & Johnson - development
DDC (HIVID; HIV-infection) - Hoffmann-La Roche - on market
DDI (Videx; HIV-infection) - Bristol-Myers Squibb - on market
dental adhesives - Amer. Dental Assoc. - clinical trials
dental resins - Amer. Dental Assoc. - clinical trials
dlk gene/proteins (cancer) - ImClone Systems - development
DNA fragment sizing - Molecular Technologies - development
dopamine D1 receptors (neurological) - Receptor Genetics - development
dopamine D2 receptors (neurological) - Receptor Genetics - BioSignal - development
drug testing immunoassays - U.S. Drug Testing Inc. - on market
DS-4152 (Kaposi's sarcoma) - Daiichi Pharm. - clinical trials
erbB-3 oncogene immunotoxins (cancer) - Protein Design Labs. - Argonex (Oncologix) - development
fetal cell line (transplantation) - Pro-Virus - development
fetal heart monitors - Veatronics - development
flow immunosensors - Dexcil - U.S. Alcohol Testing of America - development
fluoro-dideoxynucleosides (HIV-infection) - U.S. Bioscience - development
fungal toxins - Biotechnology R&D Corp. - development
gene sequencing methods - Hyseq - development
gene therapy, ex vivo - Gene Therapy Inc./Sandoz - clinical trials
gonorrhea vaccines, oral - Virus Research Institute - development
hCG-beta (hormone) - Berlex/Schering AG - development
hepatitis C virus - Chiron Corp. - Genelabs Technologies - diagnostics on market; others in development
hepatitis E virus (diagnostics and vaccines) - Genelabs Technologies - SmithKline Beecham - Abbott Labs. - Diagnostic Biotechnology (Pte) - development
hexamethylene bis(acetamide) (cancer) - Roberts Pharm. - development
HIV (immunodiagnostics) - 37 licensees - on market
HIV gp120 peptide vaccines - MedImmune - development
HIV vaccines, liposomal (development) - MedImmune
hyperthermia apparatus (cancer) - Electronic Health Technologies - development
infant formula - Oryx Resources - development
Interleukin-2 (HIV-infection - Chiron Corp. - clinical trials
interleukin-4 - Alexion - development
keratinocyte growth factor - Amgen - development
L-amino acid mustards (cancer) - Roberts Pharm. - development
laminin receptor peptides (cancer) - Monsanto - development
leukocyte implants, brain (neurological) - Phoenix Regenerative Tech. - development
Lewis Y antigen immunotoxins (cancer) - Boehringer Mannheim - Pharmacia - development
light scattering disease diagnostic imaging - FONET - clinical trials
lipid A (vaccine adjuvants) - Univax Biologics - development
lipid microstructures - Biocompatibles - development
lipospheres (vaccine delivery) - SCIOS-Nova Corp. - development
Lyme disease vaccines - Cambridge Biotech - clinical trials
macrophage stimulating protein (immune modulator) - Toyobo - development
magainins (antibacterial; antiviral) - Magainin Pharmaceuticals - clinical trials
malaria vaccines (Pfs25) - Chiron Corp. - clinical trials
metalloproteinase inhibitors (cancer) - Argonex (Oncologix) - Oncogene Sciences - development
naphthoquinones (HIV-infection) - AMRAD Corp. - development
neutrophil chemotactic factor (cancer and infectious diseases) - Chugai Pharm. - Dainippon - development
neutrophil chemotactic factor - Chugai Pharm. - development
nitric oxide prodrugs (neurological) - Comedicus Inc. - development
NMDA antagonists - Symphony Pharm. - clinical trials
Oatrim (food fat substitute) - ConAgra - Quaker Oats - on market
oncoimmunins (cancer treatment) - OncoImmunin - development
paramyxovirus culture - Bxter Healthcare Corp. - development
parvovirus vaccines - MedImmune - clinical trials
Peptide T (psoriasis; neuroleptic; Chronic Fatigue Syndrome) - Therapeutic Peptides - Advanced Peptides - clinical trials
pertussis toxin, accelular vaccines - North Amer. Vaccine - U.S. approval soon
phenserine deriv. (neurological) - CURE, Inc. - development
phototherapy (neurological; immunodeficiency) - Bio-Brite - on market
Plasmodium genes (malaria) - Becton Dickinson - development
porphyrin conjugates (cancer diagnostics) - Biomoda, Inc. - clinical trials
Protein C, transgenic (thrombolytic) - American Red Cross - development
protein crytallization - Instrumentation Technology Assoc. - development
Radinyl (radiation protection) - Roberts Pharm.(DuPont-Merck Pharm.; Taisho) - on market
radioimmune conjugates - Coulter - on market
radiolabeled red blood cells (radiodiagnostics) - Mallinkrodt Medical - on market
resiniferatoxins (pain treatments) - Afferon - development
respiratory syncytial virus immune globulin (RSV-IG) - MedImmune - U.S. approval soon
respiratory syncytial virus vaccines - American Home Products - clinical trials
retinal funduscopy - Krug Life Sciences - development
retroviral vectors - Genetic Therapy Inc./Sandoz - clinical trials
rhenium-188 radioimmune conjugates (radiodiagnostics) - Immunomedics - development
rickettsia diagnostics - Focus/MRL - on market
secretory leukocyte protease inhibitor (HIV-infection) - Synergen - development
skin scanners, ultrasound imaging - Cantwell Inc. - on market
somatostatin-28 receptor - Sandoz Ltd. - development
Staphylococcus vaccines - Univax Biologics - clinical trials
stem cell culture (cell and gene therapies) - Cellco - clinical trials
taxol culture (cancer treatment) - Phyton Catalystica - development
thiocolchicines (cancer treatment) - Advanced Biofactures - development
thyroid stimulating hormone (Thyrogen) - Genzyme - clinical trials
transferrin receptor immunotoxins (cancer treatment) - Hafslund Nycomed - development
transforming growth factor-beta (healing) - Genentech - Celtrix Pharmaceuticals - DePuy (Boehringer Mannheim) - Escalon Ophthalmics - Genzyme Corp. - clinical trials
tumor cell encapsulation (screening) - Spectrum Medical Industries - on market
tumor infiltrating lymphocytes (TIL) - Applied Immune Systems - clinical trials
typhoid fever vaccines - Connaught Labs. - Univax Biologics - development
vaccine adjuvants - Pharmos Corp. - development
vaccinia virus vectors (T7) - SmithKline Beecham - Upjohn Co. - Chiron Corp. - used internally
Whole Chromosome Paints - Imagenics - Life Technologies - on market
x-ray methods - Radical Corp. - development